Morphogenesis and self-organization of cell aggregates


Tuesday, 30 May, 2017 - 14:00

Speaker: Dr Roberto Natalini
Affiliation: Istituto per le Applicazioni del Calcolo - Consiglio Nazionale delle Ricerche

Date: Tuesday, May 30, 2017
Time: 2pm
Place: Room A-005, SISSA main campus, Via Bonomea 265, 34136 Trieste
Abstract: In this talk we present a class of discrete in continuous mathematical models, which describe self-organization phenomena for some different classes of stem cells. Our models try to mimic  the
results obtained in recent biological experiments. We rely on a hybrid description: discrete for the cellular level and continuous for the molecular level. Two case studies are considered: the formation of neuromastes in the posterior lateral line of zebrafishes, and the growth of the so called cardiospheres, which are composed by the precursors of human cardiac cells. For a simple casy we prove the existence of steady solutions consistent with the formation of particular biological structure.